Ccl4 3d Model. There are many ways to induce nafld nash for preclinical rodent modeling methods include dietary manipulation employing high fat high cholesterol high fructose methionine choline deficient diets or combinations of the above chemotoxic agent induction and acute liver injury models. For understanding the physical and chemical properties of this organic compound it is vital to know.
A ccl4 lewis structure is a diagram that represents the electron configuration of covalently bonded compounds lewis structures are meant to provide a visualization of the atomic structure and the distribution of electrons in a given chemical compound. Carbon tetrachloride was first synthesized as a by product in the synthesis of chloroform. For understanding the physical and chemical properties of this organic compound it is vital to know.
Carbon tetrachloride also known by many other names such as tetrachloromethane also recognised by the iupac carbon tet in the cleaning industry halon 104 in firefighting and refrigerant 10 in hvacr is an organic compound with the chemical formula ccl 4 it is a colourless liquid with a sweet smell that can be detected at low levels.
Ccl4 treatment in mice causes significant fibrosis within a relatively short treatment period and it is still occasionally utilised for testing drugs that target the fibrotic aspect of nash. A quick explanation of the molecular geometry of ccl4 including a description of the ccl4 bond angles looking at the ccl4 lewis structure we can see that the. The compound has a chemical formula of ccl4 and is now banned from use as it has some toxic properties that can harm the central nervous system of humans. One of the first animal models used for nafld drug discovery was the carbon tetrachloride ccl4 model introduced in the 1970s.
